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antibody sirna conjugate - Conjugation is a process in which two...

Wed, 11 Aug 2021 09:41:15 GMT

antibody sirna conjugate - Conjugation is a process in which two molecules/polymers or biomolecules/biopolymers are covalently linked together. Studies have shown that antibody molecules have many functional groups suitable for modification or conjugation purposes. Antibody-oligonucleotide conjugates or AOC belong to a class of chimeric molecules that bind to two important families of biomolecules: monoclonal antibodies and oligonucleotides. Cross-linked oligonucleotides-antibodies can be achieved by lysine and N-terminal groups. The combination of the excellent targeting ability of monoclonal antibodies and many functional forms of oligonucleotides has achieved fruitful results in various applications of AOC, including imaging, detection and targeted therapy.

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conjugate bind - BOC Sciences not only provides the synthesis of small...

Fri, 11 Jun 2021 08:35:01 GMT

conjugate bind - BOC Sciences not only provides the synthesis of small molecules and biopolymers, but also contributes to functionalization or activation of compounds ready for cross-linking with pre-activated small molecules. These small molecules are either supplied by customers or prepared internally. After labeling biopolymers with small molecules, the standard desalination, purification, quality inspection, final concentration and labeling rate were determined. BOC Sciences specializes in synthesizing new small molecules, modifying existing molecules, and advising customers on appropriate ways to activate small molecules, label small molecules, and combine small molecules with biomolecules. As one of the pioneers of synthetic biological services, we are actively seeking to develop new technologies to help customers develop new biological binding reagents for sensitive testing applications. BOC Sciences is committed to supplying cost-effective products and services, which are being utilized by our customers worldwide in drug discovery and research on a daily basis to promote innovations in various industries.

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conjugate solution chemistry - BOC Sciences is an expert at various...

Sun, 21 Feb 2021 16:27:12 GMT

conjugate solution chemistry - BOC Sciences is an expert at various bioconjugation techniques and works closely with our customers. We can provide you with high quality standards and punctual delivery of bioconjugation services. Our professional chemistry team is well trained to focus on the bioconjugation techniques.

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how to conjugate antibodies - Both avidin and biotin can bind to proteins...

Tue, 22 Dec 2020 07:23:14 GMT

how to conjugate antibodies - Both avidin and biotin can bind to proteins (including antigens, antibodies, enzymes, etc.) and fluorescein without affecting the biological activity of the latter. An antibody molecule can couple dozens of biotin or avidin molecules, and avidin or biotin molecules can bind to enzymes or fluorescein to form a biomagnification system, which can significantly improve the sensitivity of detection. Biotin is a small molecule that binds to avidin and streptavidin with very high affinity. When used in immunohistochemical techniques, the affinity of interaction makes biotin an excellent conjugate for detection. Biotin conjugates can be used in signal amplification technology. The commonly used methods are avidin biotin labeling method (LAB), avidin-biotin bridge method (BAB) and avidin-biotin peroxidase complex method (ABC).

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