Houston, Texas @ Mapdestinations.org. Houston, the nation’s fourth largest city, is bustling with culture and energy and has recently gained recognition as America’s next great global city. The burgeoning port and railroad industry, combined with oil discovery in 1901, has induced continual surges in the city's population. In the mid-twentieth century, Houston became the home of the Texas Medical Center—the world's largest concentration of healthcare and research institutions—and NASA's Johnson Space Center, where the Mission Control Center is located.
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