In vivo Recordings, Whole-cell Patch-clamp Recordings - Brain slice preparations have enabled investigators to make intracellular/whole-cell patch recordings from neurons while applying pharmacological agents but have a disadvantage in that the normal flow of information in neural circuits is disrupted. To test the acute effect of a compound on an individual neuron or the effect of pre-treatment with a drug on the spontaneous firing activity and firing rate of multiple neurons, Acroscell performs a variety of in vivo single-cell recording studies.
|
|
